Inhibition of .beta.lactamase with 6 .beta.-(substituted methyl)

Details Inhibition of .beta.lactamase with 6 .beta.-(substituted methyl) Inhibition of .beta.lactamase with 6 .beta.-(substituted methyl)

1991-07-23

1993-04-06

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

A61K 3143

Patent

active

052004031

ABSTRACT:
Compounds of the formula I ##STR1## wherein R' is a free or esterified carboxy group or a carboxylate anion and R.sup.2 is an organic group have beta-lactamase inhibition activity. A process for the preparation of the same and pharmaceutical compositions containing these compounds are provided.

REFERENCES:
patent: 4656263 (1987-04-01), Kellogg
patent: 4847247 (1989-07-01), Thompson et al.
Tetrahydron Letters, vol. 27, pp. 4857-4860, 1986.

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