Inhibition of anoxia or hypoxia-induced, endothelium-mediated va

Details Inhibition of anoxia or hypoxia-induced, endothelium-mediated va Inhibition of anoxia or hypoxia-induced, endothelium-mediated va

1991-12-17

1993-09-28

Brown, Johnnie R.

Abrasive tool making process, material, or composition

536 71, A61K 3170

Patent

active

052486699

ABSTRACT:
This invention relates to a method for inhibiting or suppressing in an animal the contraction of vessels lined with endothelial tissue, which contractions are caused by anoxia or hypoxia. The method comprises administering to such an animal an effective therapeutic (contraction-inhibiting) amount of an avermectin class antibiotic such as ivermectin or a derivative thereof for a time period sufficient to inhibit or suppress said contractions.

REFERENCES:
patent: 4199569 (1980-04-01), Chabala et al.
patent: 4310519 (1982-01-01), Albers-Schonberg et al.

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