Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...
Reexamination Certificate
2006-02-07
2006-02-07
Nickol, Gary B. (Department: 1642)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
C424S138100, C424S139100, C424S141100, C424S155100
Reexamination Certificate
active
06994852
ABSTRACT:
Antibodies directed against an antigenic determinant of high molecular weight kininogen domain 5, particularly a determinant located in the region formed by light chain amino acids Gly(440) to Lys(502), inhibit angiogenesis.
REFERENCES:
patent: 4908431 (1990-03-01), Colman et al.
patent: 5596079 (1997-01-01), Smith et al.
patent: 5756291 (1998-05-01), Griffin et al.
patent: 5786365 (1998-07-01), Heitsch et al.
patent: 5800385 (1998-09-01), Demopulos et al.
patent: 5817748 (1998-10-01), Miller et al.
patent: 5830671 (1998-11-01), Dennis et al.
patent: 5846720 (1998-12-01), Foulkes et al.
patent: 5846821 (1998-12-01), Guerinot et al.
patent: 6245886 (2001-06-01), Halazonetis et al.
patent: 7082172 (1995-03-01), None
patent: 8208692 (1996-08-01), None
patent: WO 96/25434 (1996-08-01), None
patent: WO 96/41640 (1996-12-01), None
patent: WO 97/05258 (1997-02-01), None
patent: WO 00/27866 (2000-05-01), None
Granziero et al. (Eur. J. Immunol. 1999, 29:1127-1138).
Byers, T. (CA Journal, vol. 49, No. 6, Nov./Dec. 1999).
Lottspeich et al., “The Amino Acid Sequence of the Light Chain of Human High-Molecular-Mass Kininogen”,European Journal of Biochemistry,1985, vol. 152, pp. 307-314.
Takagaki et al., Cloning and Sequence Analysis of cDNAs for Human High Molecular Weight and Low Molecular Weight Prekininogens,The Journal of Biological Chemistry,Jul. 15, 1985, vol. 260, No. 14, pp. 8601-8609.
Kitamura et al., “Structural Organization of Human Kininogen Gene and a Model for its Evolution”,The Journal of Biological Chemistry,Jul. 15, 1985, vol. 260, No. 15, pp. 8610-8617.
Shariat-Madar et al., “Kininogen-Cytokeratin 1 Interactions in Endothelial Cell Biology”,TCM,vol. 9, No. 8, 1999.
Reddigari, et al., “Human High Molecular Weight Kininogen Binds to Human Umbilical Vein Endothelial Cells Via its Heavy and Light Chains”, The American Society of Hematology,Blood,vol. 81, No. 5 (Mar. 1), 1993, pp 1306-1311.
Auerswald et al., “Cloning, Expression, And Characterization Of Human Kininogen Domain 3”,FEBS Lettersvol. 321, No. 1, pp. 93-97, 1993.
Colman et al., Contact System: A Vascular Biology Modulator With Anticoagulant, Profibrinolytic, Antiadhesive, and Proinflammatory Attributes.Blood, 90(10):3819-3843 (Nov. 15, 1997).
R.W. Colman, et al., Abstract #701,“Inhibition Of Angiogenesis By Peptides Derived From Kininogen”,Bloodvol. 92, No. 10 Supplement 1, Nov. 15, 1998.
Heiko Herwald, et al., “Identification of an Endothelial Cell Binding Site on Kininogen Domain D3”,The Journal of Biological Chemistry,vol. 270, No. 24, pp. 14634-14641 (Jun. 16, 1995).
Satya P. Kunapuli et al.,“Deletion Mutagenesis of High Molecular Weight Kininogen Light Chain”,The Journal of Biological Chemistryvol. 268, No. 4, pp. 2486-2492 (Feb. 5, 1993).
Ahmed A.K. Hasan, et al., “Mapping the Cell Binding Site on High Molecular Weight Kininogen Domain 5”,The Journal of Biological Chemistry,vo. 270, No. 33 pp. 19256-19261 (Aug. 18, 1995).
Robert W. Colman, et al., “Binding of High Molecular Weight Kininogen to Human Endothelial Cells Is Mediated via a Site within domains 2 and 3 of the Urokinase Receptor”,J. Clin. Invest.,vol. 100, No. 6, pp. 1481-1487 (Sep. 1997).
A.K. Hasan, et al., “The Carboxyl Terminus of Bradykinin and Amino Terminus of the Light Chain of Kininogens comprise an Endothelial Cell Binding Domain”, AhmedThe Journal of Biological Chemistry,vo. 269, No. 50, pp. 31822-31830 (Dec. 16, 1994).
Mohammad M.H. Khan et al.,“Three noncintiguous peptides comprise binding sites on high-molecular-weight kininogen to neutrophils”,The American Physiological Society(Heart Circ. Physiol. 44): H145-150, vol. 275 (1998).
Yanina T. Wachtfogel et al.,“High Molecular Weight Kininogen Binds to Mac-I on Neutrophils by Its Heavy Chain (Domain 3) and Its Light Chain (Domain 5)”,The Journal of Biological Chemistry,vol. 269, No. 30, pp. 19307-19312 (Jul. 29, 1994).
Shinji Asakura et al., “Inhibition of Cell Adhesion by High Molecular Weight Kininogen”,The Journal of Cell Biology,vol. 116, No. 2, pp. 465-476 (Jan. 1992).
Colman et al., Domain 5 of High Molecular Weight Kininogen (Kininostatin) Down-Regulates Endothelial Cell Proliferation and Migration and Inhibits Angiogenesis.Blood,Jan. 15, 2000, vol. 95, No. 2, pp 543-550.
Jörg Kaufmann et al., “Structural Dissection of the Multidomain Kininogens”,The Journal of Biological Chemistry,vol. 268, No. 12, Apr. 25, pp. 9079-9091.
Alvin H. Schmaier et al., “Determination of the Bifunctional Properties of High Molecular Weight Kininogen by Studies with Monoclonal Antibodies Directed to Each of Its Chains”,The Journal of Biological Chemistry,vol. 262, No. 3, Issue of Jan. 25, pp 1405-1411, 1987.
Sesha R. Reddigari, et al., “Monoclonal Antibody to Human High-Molecular-Weight Kininogen Recognizes Its Prekallikrein Binding Site and Inhibits Its Coagulant Activity”,Blood,vol. 74, No. 2, Aug. 1, 1989, pp. 695-702.
Colman Robert W.
Mousa Shaker A.
Bristol-Myers Squibb Pharma Company
Drinker Biddle & Reath LLP
Nickol Gary B.
Temple University-of the Commonwealth System of Higher Education
LandOfFree
Inhibition of angiogenesis by antibodies against high... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Inhibition of angiogenesis by antibodies against high..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibition of angiogenesis by antibodies against high... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3633453