Inhibition of alcohol metabolism by tetramethylene sulfoxides

Details Inhibition of alcohol metabolism by tetramethylene sulfoxides Inhibition of alcohol metabolism by tetramethylene sulfoxides

1983-10-17

1984-11-13

Siegel, Alan

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Allergen or component thereof

549 29, A61K 3138, C07D33300

Patent

active

044825684

ABSTRACT:
Tetramethylene sulfoxide and its substituted derivatives have been found to be exceptionally potent inhibitors of oxidation of alcohols by liver alcohol dehydrogenases.

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Chem. Abst., vol. 78, 130174f.
Sharkawi, N., (1979), Toxicology Letters 4, 493-497, Zaiken, V. G., Trusora, E. A. and Shcherbakova, L. P.
(1978), Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 176-181, Feb. 1978, [Plenum Press translation UDC 543.51:527.732'818, pp. 135-140].

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