Inhibition of adherence of microorganisms to biomaterial surface

Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...

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6098901, 424423, 424461, 128898, A61M 2500

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active

057186944

ABSTRACT:
A method of inhibiting adherence of bacteria, fungus and other similar microorganisms to the surface of biomaterials is disclosed wherein biomaterials such as catheters and prosthetic devices are pretreated with a coating of a simple carbohydrate such as a mono- or di-saccharide. Intravascular catheters treated as such are shown to have significant reduction of adherence by S. epidermidis, S. aureus, Candidas and other organisms associated with nosocomial infection.

REFERENCES:
patent: 4668224 (1987-05-01), Lentz et al.
patent: 4773902 (1988-09-01), Lentz et al.
patent: 4906237 (1990-03-01), Johansson et al.
patent: 4909799 (1990-03-01), Thulesius et al.
patent: 4980374 (1990-12-01), Steudle et al.
patent: 5055455 (1991-10-01), Pier
patent: 5167960 (1992-12-01), Ito et al.
patent: 5217492 (1993-06-01), Guire et al.
patent: 5290585 (1994-03-01), Elton
patent: 5295978 (1994-03-01), Fan et al.
patent: 5360415 (1994-11-01), Yabushita et al.
patent: 5366505 (1994-11-01), Farber
patent: 5622939 (1997-04-01), Jamas et al.
Ruggieri et al., Journal of Urology, Aug. 1987, 138(2), pp. 423-426, "Inhibition of Bacterial Adherence to Catheter Latex Surfaces".
Vaudaux et al., Journal of Biomaterial, Science Polymer Addition, 1992, vol. 4, No. 2, pp. 89-97 (1992) "Inhibition by Heparin and Derivatized Dextrans of Staphylococcus Aureus Adhesion to Fibronectin-Coated Biomaterials".
Rupp, Hemagglutination and Adherence to Plastic by Staphylococcus Epidermidis (Infection and Immunity, Oct. 1992) vol. 60, No. 10, pp. 4322-4327.
Corona, Subspecialty Clinics: Critical-Care Medicine Infections Related to Central Venous Catheter (Mayo Clin. Proc 1990) 65:979-986.
Goldmann, Pathogenesis of Infections Related to Intravascular Catherization (Clinical Microbiology Rev 1993) pp. 176-192.
Gristina, Biomaterial-Centered Infection: Microbial Adhesion Versus Tissue Integration (Science Sep. 1987) vol. 237, pp. 1588-1595.
Hussain et al., JID Mar. 1991:163 "Isolation and Composition of the Extracellular Slime Made by Coagulase-Negative Staphylococci in a Chemically Defined Medium".
Christensen, et al., Infection and Immunity, Sep. 1990, vo. 58, No. 9:2906-2911 "Identification of an Antigenic Marker of Slime Production for Staphlococcus Epidermidis".
Drewry, et al., J. Clin. Microbi. Jun. 1990 vo. 28, No. 6:1292-1296 "Staphylococcal Slime: A Cautionary Tale".

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