Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1994-05-19
1996-09-17
Criares, Theodore J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514216, 5142235, 5142255, 5142245, 514282, 5142312, 514304, 514305, 514306, 514307, 514812, A61K 3170, A61K 3154, A61K 3144, A61K 31445
Patent
active
055568386
ABSTRACT:
Nontoxic substances that block the N-methyl-D-aspartate (NMDA) receptor, e.g., a morphinan such as dextromethorphan or dextrorphan, or that block a major intracellular consequence of NMDA-receptor activation, e.g., a ganglioside such as GM.sub.1 or GT.sub.1b, a phenothiazine such as trifluoperazine or a naphthalenesulfonamide such as N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, inhibit the development of tolerance to and/or dependence on addictive drugs, e.g., narcotic analgesics such as morphine, codeine, etc.
REFERENCES:
Pharmacol. Biochem. Behav. vol. 35, No. 4 (1990), pp. 829-832.
Pharmacol. Biochem. Behav. vol. 43, No. 2 (1992), pp. 487-490.
Dtsch. Apoth.-Ztg. vol. 119, No. 21 (1979), p. 821, "Opiat-Rezeptoren und Endorphine".
Truillo et al.; "Inhibition of Morphine . . . MIC801"; Science; vol. 251, pp. 84-87.
Marek et al; "Brain Research, Delayed application of MIC801 . . . in rats."; vol. 558, pp. 163-165.
Lyle John W.
Mao Jianren
Mayer David J.
Price Donald D.
Criares Theodore J.
Virginia Commonwealth University
LandOfFree
Inhibiting the development of tolerance to and/or dependence on does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Inhibiting the development of tolerance to and/or dependence on , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibiting the development of tolerance to and/or dependence on will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-413097