Inhibiting of tumor growth with an antagonist of the renin-angio

Details Inhibiting of tumor growth with an antagonist of the renin-angio Inhibiting of tumor growth with an antagonist of the renin-angio

1988-05-04

1990-02-06

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424423, 424426, A61F 1300

Patent

active

048987328

ABSTRACT:
A method of inhibiting tumor growth in a patient which comprises administering to the patient an effective dose of a pharmaceutical antagonist of the renin-angiotensin system of the patient.

REFERENCES:
patent: 3932624 (1976-01-01), Fulton
patent: 4416595 (1983-11-01), Cromie
Dominic Bazuck et al., Diagnosis and Treatment of Renin-Secreting Tumors, etc., vol. 6, No. 5, Sep.-Oct. 1984, pp. 760-766.
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Diagnostic Product Information concerning saralasin acetate, pp. 3011-3013.
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Jane L. Frederick, M.D. et al., Initiation of Angiogenesis by Porcine Follicular Fluid, American Journal of Obstet Gynecol, Aug. 15, 1985, vol. 152, No. 8, pp. 1073-1078.
Fernandez et al., Angiotensin II Decreases Mortality Rate in Gerbils with Unilateral Carotid Ligation, Stroke vol. 17, No. 1, Jan.-Feb., 1986, pp. 82-85.
Fernandez et al., Renin in Angiolymphoid Hyperplasia with Eosinophilia Arch. Pathol. Lab. Med., vol. 110, Dec., 1986, pp. 1131-1135.
Fernandez et al., Neovascularization Produced by Angiotensin II, The Journal of Laboratory and Clinical Medicine, vol. 105, No. 2, pp. 141-145, Feb., 1985.
Dominique Baruch et al., Diagnosis and Treatment of Renin-Secreting Tumors, Report of Three Cases, Hypertension Case Reports, vol. 6, No. 5, Sep.-Oct., 1984, pp. 760-766.
Michael J. Peach, Renin-Angiotensin System: Biochemistry and Mechanisms of Action, Physiological Reviews, vol. 57, No. 2, Apr., 1977, pp. 313-370.
John B. Kostis et al., Angiotensin Converting Enzyme Inhibitors, Alan R. Liss, Inc., New York, pp. 213-261, (1987).

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