Inhibiting growth and spread of malignancy and retarding DNA bre

Details Inhibiting growth and spread of malignancy and retarding DNA bre Inhibiting growth and spread of malignancy and retarding DNA bre

1996-09-16

1998-04-28

Spivack, Phyllis G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

A61K 3119

Patent

active

057444986

ABSTRACT:
Growth of an adenocarcinoma in the liver, lung, lymph node or mammary tissue in a mammal can be inhibited by orally administering a therapeutically effective dosage of pyruvate in the form of sodium pyruvate, calcium pyruvate or organic esters of pyruvate. The pyruvate treatment also retards the development of breaks in the DNA strands associated with the malignancy.

REFERENCES:
patent: 4158057 (1979-06-01), Stanko
patent: 4351835 (1982-09-01), Stanko
patent: 4415576 (1983-11-01), Stanko
patent: 4548937 (1985-10-01), Stanko
patent: 4812479 (1989-03-01), Stanko
patent: 4874790 (1989-10-01), Stanko
patent: 5134162 (1992-07-01), Stanko
patent: 5256697 (1993-10-01), Miller et al.
patent: 5283260 (1994-02-01), Miller et al.
patent: 5294641 (1994-03-01), Stanko
O'Donnell-Tormey, et al., J. Exp. Med. (1987 Feb. 1), 165(2), 500-14.
Olivotto, et al., Toxicol. Pathol. (1984), 12(4), 369-73.
Stanko, et al., Pyruvate Inhibits Growth of Mammary Adenocarcinoma 13742 in Rats, Cancer Research 54, 1004-7, 1994.
Kroll et al., Biosciences 41(7-8), pp. 787-794, (1986).

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