Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Skin burn or open wound treatment
Patent
1998-09-01
2000-03-21
Harrison, Robert H.
Drug, bio-affecting and body treating compositions
Topical body preparation containing solid synthetic organic...
Skin burn or open wound treatment
424 7808, 424 7835, 424 7837, 424443, 424445, A61K 31785, A61F 1300
Patent
active
060399406
ABSTRACT:
A composition and method for treating a wound with an inherently antimicrobial dressing. The dressing is a hydrogel containing from about 15 to 95 percent, and preferably from about 61 to 90 percent, by weight of a cationic quaternary amine acrylate polymer prepared by the polymerization of acryloyloxyethyl(or propyl)-trialkyl(or aryl)-substituted ammonium salts or acrylamidoethyl(or propyl)-trialkyl(or aryl)-substituted ammonium salts. The antimicrobial hydrogels are non-irritating to the wound, absorb wound exudate, and, due to the inherently antimicrobial properties, enhance the sterile environment around the wound. The hydrogels have sufficient adhesive properties that loose contact with the wound is assured but can also be removed without leaving any gel residue on the wound. The wound dressings are preferably formed on a substrate, such as a web or patch, for ease in application to and removal from the wound. If desired, additional antimicrobial or other pharmaceutically active agents can also be incorporated into the hydrogel structure.
REFERENCES:
patent: 3898188 (1975-08-01), Rembaum et al.
patent: 3975350 (1976-08-01), Hudgin et al.
patent: 4119094 (1978-10-01), Micklus et al.
patent: 4191743 (1980-03-01), Klemm et al.
patent: 4226232 (1980-10-01), Spence
patent: 4318947 (1982-03-01), Joung
patent: 4373009 (1983-02-01), Winn
patent: 4393048 (1983-07-01), Mason, Jr. et al.
patent: 4515593 (1985-05-01), Norton
patent: 4563184 (1986-01-01), Korol
patent: 4570629 (1986-02-01), Widra
patent: 4657006 (1987-04-01), Rawlings et al.
patent: 4705709 (1987-11-01), Vailancourt
patent: 4728323 (1988-03-01), Matson
patent: 4769013 (1988-09-01), Lorenz et al.
patent: 4791063 (1988-12-01), Hou et al.
patent: 5004760 (1991-04-01), Patton et al.
patent: 5006267 (1991-04-01), Vaughn et al.
patent: 5019096 (1991-05-01), Fox, Jr. et al.
patent: 5069907 (1991-12-01), Mixon et al.
patent: 5082697 (1992-01-01), Patton et al.
patent: 5269770 (1993-12-01), Conway et al.
patent: 5432000 (1995-07-01), Young, Sr. et al.
patent: 5498478 (1996-03-01), Hansen et al.
patent: 5512329 (1996-04-01), Guire et al.
patent: 5563056 (1996-10-01), Swan et al.
patent: 5599321 (1997-02-01), Conway et al.
patent: 5624704 (1997-04-01), Darouiche et al.
patent: 5670557 (1997-09-01), Dietz et al.
patent: 5674561 (1997-10-01), Dietz et al.
patent: 5800685 (1998-09-01), Perrault
I. I. Raad, "Vascular Catheters Impregnated with Antimicrobial Agents: Present Knowledge and Future Direction," Infection Control and Hospital Epidemiology, 18(4): 227-229 (1997).
R. O. Darouiche, H. Safar, and I. I. Raad, "In Vitro Efficacy of Antimicrobial-Coated Bladder Catheters in Inhibiting Bacterial Migration along Catheter Surface," J. Infect. Dis., 176: 1109-12 (1997).
W. Kohen and B. Jansen, "Polymer Materials for the Prevention of Catheter-related Infections," Zbl. Bakt., 283: 175-186 (1995).
Perrault James J.
Rouns Cameron G.
Ballard Medical Products
Harrison Robert H.
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