Inhaler apparatus with modified surfaces for enhanced release of

Details Inhaler apparatus with modified surfaces for enhanced release of Inhaler apparatus with modified surfaces for enhanced release of

1996-06-10

1999-02-16

Weiss, John G.

Surgery

Respiratory method or device

Means for mixing treating agent with respiratory gas

12820312, A61M 1500

Patent

active

058710108

ABSTRACT:
In one aspect, the present invention provides an inhaler apparatus comprising interior surfaces having contact with a medicament for inhalation, the interior surfaces including an interior surface of a mouthpiece and a substrate with medicament deposited thereon at least one of such interior surfaces comprising indentations or raised areas therein, the raised areas having valleys therebetween. In certain preferred embodiments, the interior surface is a surface on a substrate having medicament deposited thereon, and in other preferred embodiments, the interior surface is an interior surface of the mouthpiece of the inhaler. In addition to providing surface topology for minimizing the area of contact between the medicament and the surfaces of the inhaler, the surfaces are preferably made of a material having a low surface energy, and more preferably, also having, when uncharged, no substantial van der Waals or electrostatic interaction with the medicament. Furthermore, the material is preferably substantially chemically unreactive with the medicament.

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