Inhalation pharmaceuticals

Details Inhalation pharmaceuticals Inhalation pharmaceuticals

1984-05-03

1986-05-20

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514826, 514951, A61K 3135

Patent

active

045902062

ABSTRACT:
There is described a finely divided inhalation drug, e.g. sodium cromoglycate, comprising a therapeutically effective proportion of individual particles capable of penetrating deep into the lung, characterized in that a bulk of the particles which is both unagglomerated and unmixed with a coarse carrier, is sufficiently free flowing to be filled into capsules on an automatic filling machine and to empty from an opened capsule in an inhalation device. A number of the individual drug particles have a spherical, collapsed spherical or ring doughnut shape.
There is also described a method of making the fine particles and pharmaceutical formulations containing them.

REFERENCES:
patent: 3957965 (1976-05-01), Hartley et al.
patent: 4161516 (1979-07-01), Bell
Lachman et al., "The Theory and Practice of Industrial Pharmacy", 2nd ed., 1978, pp. 519-524.

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