Surgery – Liquid medicament atomizer or sprayer – Pre-pressurized container holding medicament
Patent
1984-10-25
1987-05-12
Recla, Henry J.
Surgery
Liquid medicament atomizer or sprayer
Pre-pressurized container holding medicament
12820315, 604 58, A61M 1500
Patent
active
046641076
DESCRIPTION:
BRIEF SUMMARY
TECHNICAL FIELD
This invention relates to inhalation activatable dispensers for use with aerosol container assemblies which contain medicaments for inhalation therapy, are pressurized with liquid propellants, and include a metering valve through which a series of metered medicament doses can be dispensed.
BACKGROUND ART
Inhalation activatable dispensers for use with aerosol container assemblies of the type described above are well known, their general purpose being to afford proper coordination of the dispensing of a dose of medicament with the inhalation of the patient to allow the maximum proportion of the dose of medicament to be drawn into the patient's bronchial passages. Examples of such dispensers are described in British Patent Specification Nos. 1,269,554, 1,335,378, 1,392,192 and 2,061,116 and U.S. Pat. Nos. 3,456,644, 3,456,645, 3,456,646, 3,565,070, 3,598,294, 3,814,297, 3,605,738, 3,732,864, 3,636,949, 3,789,843 and 3,187,748.
DISCLOSURE OF THE INVENTION
The present invention provides a new and improved inhalation activatable dispenser which is more simple and difficult to misuse than known prior art dispensers.
According to the present invention, there is provided an inhalation activatable dispenser for use with an aerosol container assembly including a metering valve for dispensing medicament from a container included in the assembly, which valve includes a hollow stem which is movable relative to the rest of the valve and the container between an outer closed position to which the stem is biased by a valve spring, and an inner position at which a metered dose of medicament is dispensed from the valve through the stem. The dispenser has a housing formed with a through air passage terminating at a mouthpiece. The housing is adapted to receive the container assembly with the stem in a support block with a through orifice communicating with the air passage and affords the application of a force sufficient to move the valve stem to its inner discharge position in opposition to the valve spring. A latch mechanism is provided comprising a vane disposed in the air passage and movable upon inhalation at the mouthpiece from a blocking position across the air passage at which the latch mechanism is engaged and prevents relative movement between the container and support block in response to the force, and a non-blocking position at one side of the air passage at which the latch mechanism affords such movement in response to the force. The dispenser is operable to dispense aerosol into the air passage by the sequential operations of: applying such a force when the vane is in its blocking position; and inhaling at the mouthpiece, causing movement of the vane to its non-blocking position which releases the lock mechanism and allows the force to move the stem relative to the container to dispense aerosol into the air passage for inhalation by the user.
In the present invention the vane is pivotally mounted in the air passage between the orifice and the mouthpiece. Such location of the vane allows the dispenser to have a small overall size, allows an air inlet for the air passage to be located close to the mouthpiece so that the air inlet and mouthpiece can be closed by a single cover, and separates the container and any moving parts other than the vane from the air passage to minimize the chances of foreign matter being inhaled. Also this position of the vane affords the use of locking means such as a projection on the mouthpiece cover to positively restrain movement of the vane when the dispenser is not in use.
Also in the present invention the latch mechanism includes means which prevent its release to dispense a dose of medicament into the air passage when the vane is in its non-blocking position prior to the application of the force in the dispenser. Thus, it is ensured that the patient cannot commence inhalation too soon before the dose is dispensed and thereby draw an inadequate proportion of the dose into the bronchial passages. Dispensing of a dose only occurs upon inhalation if the force i
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patent: 3456644 (1969-07-01), Thiel
patent: 3456645 (1969-07-01), Brock
patent: 3456646 (1969-07-01), Phillips et al.
patent: 3565070 (1971-02-01), Hanson et al.
patent: 3598294 (1971-08-01), Hedrick et al.
patent: 3605738 (1971-09-01), Ciranna
patent: 3636949 (1972-01-01), Kropp
patent: 3732864 (1973-05-01), Thompson et al.
patent: 3789843 (1974-02-01), Armstrong et al.
patent: 3814297 (1974-06-01), Warren
Huebsch William L.
Minnesota Mining and Manufacturing Company
Recla Henry J.
Sell Donald M.
Smith James A.
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