Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid
Reexamination Certificate
2005-05-10
2005-05-10
Kunz, Gary (Department: 1616)
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
Organic pressurized fluid
C424S400000, C514S826000, C514S217050, C514S291000, C514S171000, C239S333000, C128S200140
Reexamination Certificate
active
06890517
ABSTRACT:
A liquid, propellant-free pharmaceutical preparation comprising:(a) a first active substance comprising a tiotropium salt, in a concentration based on tiotropium of between 0.0005% and 5% by weight;(b) a second active substance selected from the group consisting of: an antiallergic, antihistamine, steroid, and leukotriene antagonist;(c) a solvent selected from water or a water/ethanol mixture; and(d) a pharmacologically acceptable preservative,wherein the pH of the preparation is adjusted to between 2.0 and 4.5 with an acid and the tiotropium salt is dissolved in the solvent,optionally including a pharmacologically acceptable complexing agent, stabilizer, a pharmacologically acceptable cosolvent, or other pharmacologically acceptable adjuvants and additives; a method for administering a pharmaceutical preparation by nebulizing the pharmaceutical preparation in an inhaler, and a method of treating asthma or COPD in a patient using the pharmaceutical preparation.
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Barth Petra
Drechsel Karin
Niklaus-Humke Barbara
Schmelzer Christel
Boehringer Ingelheim Pharma KG
Devlin Mary-Ellen M.
Haghighatian Mina
Kunz Gary
Morris Michael P.
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