Ingestible device for the release of substances at distinct...

Surgery – Controlled release therapeutic device or system

Reexamination Certificate

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C604S093010, C600S007000

Reexamination Certificate

active

06884239

ABSTRACT:
The field of the invention is site-specific drug delivery capsules (SSDC's). The disclosure relates to a closure member (14) for a substance reservoir (12) of an SSDC (10). The SSDC (10) includes a retainer that provides a non-linear force resisting opening of the closure member (14). The non-linear force ensures that the closure member (14) unseals the reservoir (12) only when an opening force exceeds a maximal value of the resisting force, thereby preventing premature or accidental emptying of the reservoir (12). The preferred means of providing the resistive force is a rolling, elastomeric o-ring (64) that additionally seals the closure member (14) into an aperture (13).

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patent: 4507115 (1985-03-01), Kambara et al.
patent: 5279607 (1994-01-01), Schentag et al.
patent: 6632216 (2003-10-01), Houzego et al.
patent: 0 715 847 (1996-06-01), None
Lambert, et al., “Autonomous telemetric capsule to explore the small bowel,”Medical&Biological Engineering&Computing29(2):191-196 (1991).

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