INGAP protein involved in pancreatic islet neogenesis

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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C435S069100, C435S007100, C435S006120, C435S320100, C435S252300, C435S325000, C536S023100, C536S023500, C536S024100, C530S350000

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RE039062

ABSTRACT:
Cellophane wrapping (CW) of hamster pancreas induces proliferation of duct epithelial cells followed by endocrine cell differentiation and islet neogenesis. Using the mRNA differential display technique a cDNA clone expressed in cellophane wrapped but not in control pancreata was identified. Using this cDNA as a probe, a cDNA library was screened and a gene not previously described was identified and named INGAP.

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