Ingap protein involved in pancreatic islet neogenesis

Details Ingap protein involved in pancreatic islet neogenesis Ingap protein involved in pancreatic islet neogenesis

1996-09-09

1998-11-24

Grimes, Eric

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4352523, 536 231, 536 235, 536 243, 4241851, C12N 1500

Patent

active

058405313

ABSTRACT:
Cellophane wrapping (CW) of hamster pancreas induces proliferation of duct epithelial cells followed by endocrine cell differentiation and islet neogenesis. Using the mRNA differential display technique a cDNA clone expressed in cellophane wrapped but not in control pancreata was identified. Using this cDNA as a probe, a cDNA library was screened and a gene not previously described was identified and named INGAP.

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