Ingap protein involved in pancreatic islet neogenesis

Details Ingap protein involved in pancreatic islet neogenesis Ingap protein involved in pancreatic islet neogenesis

1995-02-22

1998-11-10

Wax, Robert A.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530412, 514 12, 514 13, 514 14, 4241981, 435 697, C07K 1400

Patent

active

058345906

ABSTRACT:
Cellophane wrapping (CW) of hamster pancreas induces proliferation of duct epithelial cells followed by endocrine cell differentiation and islet neogenesis. Using the mRNA differential display technique a cDNA clone expressed in cellophane wrapped but not in control pancreata was identified. Using this cDNA as a probe, a cDNA library was screened and a gene not previously described was identified and named INGAP.

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