Infusion preparation comprising phospholipid

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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424400, A61K 9127

Patent

active

056745273

ABSTRACT:
Disclosed is an infusion preparation for nutrient supply use. It comprises a sugar, amino acids, electrolytes and a fat emulsion. It has an excellent shelf life without causing precipitation, denaturation and the like in spite of the simultaneous presence of these components. Also disclosed is a container filled with infusion liquids comprising a first and a second compartments separated from each other by a separation means, wherein an infusion liquid containing a fat emulsion and a sugar is included in the first compartment and another infusion liquid containing amino acids and electrolytes is included in the second compartment. Further disclosed are an infusion preparation comprising a fat emulsion and a sugar, and an infusion preparation comprising amino acids and electrolytes. An infusion preparation containing a sugar, amino acids, electrolytes and a fat emulsion can be obtained easily and aseptically upon use, by simply removing a separation means attached to the container and mixing the two infusion liquids.

REFERENCES:
patent: 4604286 (1986-08-01), Kawajiri
patent: 4871550 (1989-10-01), Millman
patent: 4976707 (1990-12-01), Bodicky et al.
patent: 5032608 (1991-07-01), Dudrick
Chemical Abstract vol. 111, 1989 p. 312 #111:219205q.
Kachorovski, B.V. Chemical Abstracts, vol. 89, 1978, #80189.
Muchtar et al., Chemical Abstracts, vol. 111, 1989, #219205.
Ishii, Chemical Abstracts, vol. 113, 1990, #197839.
Database WPIL, Section Ch, Week 8618, for JP-A-61-058560.
143826 Jun. 6, 1989 Japan with English Language Abstract.

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