Infrared thermography

Chemistry: analytical and immunological testing – Measurement includes temperature change of the material...

Reexamination Certificate

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C436S002000, C435S005000, C128S126100

Reexamination Certificate

active

06881584

ABSTRACT:
The present invention relates, in general, to thermography and, in particular, to a method of using infrared thermography to monitor physiological and molecular events that elicit a thermogenic response in animals (including humans), plants, tissues, cells and cell-free systems. The present method can be used for screening, identifying, and ranking drug candidates for multiple diseases, disorders and conditions.

REFERENCES:
patent: 2311368 (1997-09-01), None
Nedergaard and Cannon,[3H]GDP binding and thermogenin amount in brown adipose tissue mitochondria from cold-exposed rats, AM. I. Physiol. 248 (3 Pt 1): C365-3C371 (1985).
Reers et al,J-Aggregate Formation of a Carbocyanine as a Quantitative Fluorescent Indicator of Membrane Potential, Biochemistry30:4480-4486 (1991).
Bottcher and Furst,A new microcatheter enables microcalorimetric assessment of thermogenesis after stimulation in cell cultures, J. Biochem. Biophys. Methods32: 191-194 (1996).
Carr A., et al.,Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: a cohort story, Lancet353, 2093-2099 (1999).
Lenhard et al,Effects of Toglitazone and Metformin on Glucose and Lipid Metabolism, Biochem. Pharmacol. 54:801-808 (1997).
Paulik and Lenhard,Thiazolidinediones inhibit alkaline phosphatase activity while increasing expression of uncoupling protein, deiodinase, and increasing mitochodrial mass in C3H10T1/2 cells, Cell Tissue Res. 290: 79-87 (1997).
Surwit et al.,Differential Effects of Fat and Sucrose on the Development of Obesity and Diabetes in C57B1/6J and A/J Mice, Metabolism44(5): 645-651 (1995).
Ahmad-Junan et al,Synthetic studies on electron transport inhibitors related to natural products, Biochem. Soc. Trans.22:237-241 (1994).
Tereda,The Interaction of Highly Active Uncouplers with Mitochondria, Biochem. Biophys, Acta639:225-242 (1981).
Himms-Hagen,MiniReview: Role of Brown Adipose Tissue Thermogenesis in Control of Thermoregulatory Feeding in Rats: A New Hypothesis That Links Thermostatic and Glucostatic Hypotheses for Control of Food Intake, Proc. Soc. Exp. Bio. Med.208:159-169 (1995).
Ricquier et al,Molecular studies of the upcoupling protein, FASEB Journal5:2237-2242 (1991).
Fleury et al,Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia, Nat. Genet.15:206-272 (1997).
Enerback et al.,Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese, Nature387:90-94 (1997).
Shimabukuro et al,Induction of Uncoupling aProtein-2 mRNA by Troglitazone in the Pancreatic Islets of Zucker Diabetic Fatty Rats, Biochem. Biophys. Res. Commun.237:359-361 (1997).
Lehmann et al,An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor y(PPARy), J. Biol. Chem.270:12953-12956 (1995).
Tai et al,Activation of the Nuclear Receptor Peroxisome Proliferator-activated Receptor y Promotes Brown Adipocyte Differentiation, J. Biol. Chem.271:29909-29914 (1996).
Henke et al.,N-(2-Benzolylphenyl)-L-tyrosine PPARy Agonists. 1. Discovery of a Novel Series of Potent Antihyperglycemic and Antihyperlipidemic Agents, J. Med. Chem.41:5020-5036 (1998).
Blaak et al,Adrenoceptor subtypes mediating catecholamine-induced thermogenesis in man, Int. J. Obes. Relat. Metab. Disord.17 Suppl 3:S78-S81 (1993).
Rehnmark et al.,a-and B-Adrenergic Induction of the Expression of the Uncoupling Protein Thermogenin in Brown Adipocytes Differentiated in Culture, J. Biol. Chem.265:16464-16471 (1990).
Lafontan and Berlan,Fat cell adrenergic receptors and the control of white and brown fat cell function, J. Lipid Res.34:1057-1091 (1993).
Silva,Full Expression of Uncoupling Protein Gene Requires the Concurrence of Norepinephrine and Triiodothyronine, Mol. Endocrinol.2:706-713 (1988).
Rehnmark et al.,Brown Adipocytes Differentiated in Vitro Can Express the Gene for the Uncoupling Protein Thermogenin: Effects of Hypothyroidism and Norepinephrine, Exp. Cell Res.182:75-83 (1989).
Champigny and Ricquier,Evidence from in vitro differentiating cells that adrenoceptor agonists can increase uncoupling protein mRNA level in adipocytes of adult humans: an RT-PCR study, J. Lipid Res.37:1907-1914 (1996).
Scarpace, Ann.,Thermoregulation with Age: Role of Beta-Adrenergic Signal Transduction, N.y. Acad. Sci.813:111-116 (1997).
Ferreram N.,Davis-Smyth T, The Biology of Vascular Endothelial Growth Factor, Endocr. Rev.Feb. 18,1997(1):4-25.
Koenigbauer,Pharmaceutical Applications of Microcalorimetry, Pharm Res. Jun; 11(6):777-783 (1994).
Hoyeyda,Catalyst discovery through combinatorial chemistry, Chemistry & Biology, 5(8):R187-R191 (1998).
Stock, Sibutramine:a review of the pharmacology of a novel anti-obesity agent, Int. J. Obesity21:525-29 (1997).
Asrup et al.,Enhanced thermogenic responsiveness during chronic ephedrine treatment in man, Am. J. Clin. Nutr.42:183-94 (1985).
Kenakin,Lenhard and Paulik, B-Adrenoceptor Assays, Curr Prot Pharm; 1(unit 4.6):1-36 (1998).
International Search Report, PCT/US00/31755, Date of Mailing: Mar. 5, 2001.

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