Influenza virus binding, sialylated oligosaccharide...

Details Influenza virus binding, sialylated oligosaccharide... Influenza virus binding, sialylated oligosaccharide...

2011-03-08

2011-03-08

Jiang, Shaojia Anna (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S055100, C536S053000, C536S123100

Reexamination Certificate

active

07902170

ABSTRACT:
The present invention is directed to human influenza virus binding substance containing at least one oligosaccharide chain, which comprises a terminal NeuNAcα6 linked to: (a) a linear or branched polylactosamine type structure consisting of at least three lactosamine residues, a linear sequence optionally containing one or two α3-linked fucose residues in a non-sialylated lactosamine, a branched structure optionally carrying one or more additional NeuNAcα-residues at a terminal position in a branch, and/or (b) a linear or branched structure with two lactosamine and one lactose residue, a linear structure in addition containing one or two α3-linked fucose residues in a non-sialylated lactosamine or lactose, a branched structure optionally carrying one additional NeuNAcα-residue in a terminal position of the branch, or an analog or derivative of said oligosaccharide chain for use in binding of human influenza virus.

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