Influenza virus and process of producing a vaccine therefrom

Details Influenza virus and process of producing a vaccine therefrom Influenza virus and process of producing a vaccine therefrom

1981-02-04

1982-07-06

Rosen, Sam

Drug, bio-affecting and body treating compositions

Lymphokine

435235, 435236, A61K 3912, C12N 700

Patent

active

043382967

ABSTRACT:
The invention relates to a novel influenza virus strain and to the influenza virus vaccine containing said strain.
The new strain, which is the CNCM N.degree. I-099 strain, is prepared by recombination of the influenza A/PR/8/34 virus strain with the influenza A/California/10/78 (CNCM N.degree. I-098) virus strain.
The vaccine is prepared by allowing the CNCM N.degree. I-099 strain to grow in the allantoic cavity of fertile hen's eggs, harvesting and freeze-drying the yielded virus material.
The strain and the vaccine deriving therefrom are valuable for the immunization against influenza caused by influenza type A (H.sub.1 N.sub.1) virus strains.

REFERENCES:
patent: 3991179 (1976-11-01), Beare
patent: 4009258 (1977-02-01), Kilbourne

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