Influenza vaccines extemporaneously adsorbed to aluminium...

Details Influenza vaccines extemporaneously adsorbed to aluminium... Influenza vaccines extemporaneously adsorbed to aluminium...

2011-06-14

2011-06-14

Mosher, Mary E (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

C424S210100, C424S206100, C424S278100

Reexamination Certificate

active

07959931

ABSTRACT:
Antigen and adjuvant components of an adjuvanted influenza vaccine are not mixed during manufacture, but are provided as separate components for extemporaneous mixing at the time of use, for example as a kit comprising (i) an antigen component, comprising an influenza virus antigen; and (ii) an adjuvant component, comprising an aluminium salt.

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patent: WO 00/15251 (2000-03-01), None
patent: WO 01/22992 (2001-04-01), None
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Pressler K et al: “Comparison of the Anti Genicity and Tolerance of an Influenza Aluminum Oxide Adsorbate Vaccine With an Aqueous Vaccine” Pharmatherapeutica, vol. 3, No. 3, 1982, pp. 195-200.
Vanselow B A et al: “Bovine Ephemeral Fever Vaccine Incorporating Adjuvant Quil A: A Comparative Study Using Adjuvants Quil A, Aluminium Hydroxide Gel and Dextran Sulphate” Veterinary Record, British Veterinary Association, London, GB, vol. 117, No. 2, Jul. 13, 1985, pp. 37-43.
Zhang C-H et al: “Immune responses in Balb/c mice induced by a candidate SARS-CoV inactivated vaccine prepared fror F69 strain” Vaccine, Butterworth Scientific, Guildford, GB, vol. 23, No. 24, May 2, 2005, pp. 3196-3201, XP004851707.

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