Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Reexamination Certificate
2007-11-30
2010-10-05
Lucas, Zachariah (Department: 1648)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
C424S185100, C530S300000, C530S326000
Reexamination Certificate
active
07807173
ABSTRACT:
Peptide-based anti-influenza formulations against influenza are disclosed. The peptides are derived from influenza-based epitopes. The formulations are based on peptide mixtures which may be formulated so that variability is present at particular residues. The formulations can be used to prepare vaccines for preventing influenza, particularly avian influenza.
REFERENCES:
patent: 2002/0183484 (2002-12-01), Torres
patent: 2004/0223976 (2004-11-01), Bianchi et al.
patent: 03/066090 (2003-08-01), None
patent: 2006/128294 (2007-05-01), None
patent: 2007056266 (2007-05-01), None
patent: WO 2007/051036 (2007-05-01), None
Bowie et al., “Deciphering the message in protein sequences: tolerance to amino acid substitutions,” Science, vol. 247 No. 4948, pp. 1306-1310 (Mar. 1990).
Crowe et al.,“Identification of protective and non-protective T cell epitopes in influenza,” Vaccine, vol. 24 No. 4, pp. 452-456 (Jan. 2006).
GenPept ABJ51684, “hemagglutinin [Influenza A virus (A/chicken/Viet Nam/11/2005(H5N1))],” Oct. 2006.
GenPept ABJ96856, “hemagglutinin [Influenza A virus, (A/goose/Shantou/2104/2006(H5N1))],” Oct. 2006.
Hioe et al., “Overlapping cytotoxic T-lymphocyte and B-cell antigenic sites on the influenza virus H5 hemagglutinin,” Journal of Virology, vol. 64 No. 12, pp. 6246-6251 (Dec. 1990).
Mateu et al., “A single amino acid substitution affects multiple overlapping epitopes in the major antigenic site of foot-and-mouth disease virus of serotype C,” Journal of General Virology, vol. 71 No. 3, pp. 629-637 (Mar. 1990).
Riffkin et al., “A single amino-acid change between the antigenically different extracellular serine proteases V2 and B2 from Dichelobacter nodosus,” Gene, vol. 167 Nos. 1-2, pp. 179-283 (Dec. 1995).
Ha et al., “X-ray structure of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs”, Proc. National Acad. Science USA, Sep. 25, 2001, vol. 98, No. 20, pp. 11181-11186.
Kaverin et al., “Structure of antigenic sites on the hemagglutinin molecule of H5 avian influenza virus and phenotypic variation of escape mutants”, Journal Gen. Virology, Oct. 2002, vol. 83, Pt. 10, pp. 2497-2505.
Katz et al. “Pathogenesis of and immunity to avian influenza A H5 viruses”, Biomedicine and Pharmacotherapy, Elsevier, Paris, Fr., vol. 54, No. 4, May 1, 2000, pp. 178-187 XP005888635.
European Patent Application No. 07855446.6: Extended European Search Report dated Jan. 26, 2010.
Borden Ladner Gervais LLP
Lucas Zachariah
Nauman David
Variation Biotechnologies Inc.
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