Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Reexamination Certificate
2008-01-08
2008-01-08
Campell, Bruce R. (Department: 1648)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
C424S204100, C424S205100, C424S206100, C424S209100
Reexamination Certificate
active
10480952
ABSTRACT:
An inactivated influenza virus preparation is described which comprises a haemagglutinin antigen stabilized in the absence of thiomersal, or at low levels of thiomersal, wherein the haemagglutinin is detectable by a SRD assay. The influenza virus preparation may comprise a micelle modifying excipient, for example α-tocopherol or a derivative thereof in a sufficient amount to stabilize the haemagglutinin.
REFERENCES:
patent: 5472706 (1995-12-01), Friedman et al.
patent: 5616487 (1997-04-01), Eisfeld et al.
patent: 5919480 (1999-07-01), Yechezkel et al.
patent: 6156297 (2000-12-01), Mellul et al.
patent: 195 47 160 (1997-06-01), None
patent: 0 400 569 (1990-12-01), None
patent: 0 750 907 (1997-01-01), None
patent: 0 985 408 (2000-03-01), None
patent: WO95/11700 (1995-05-01), None
patent: WO98/24409 (1998-06-01), None
patent: WO98/30228 (1998-07-01), None
patent: WO98/42373 (1998-10-01), None
patent: WO98/56414 (1998-10-01), None
patent: WO98/56414 (1998-12-01), None
patent: WO99/11241 (1999-03-01), None
patent: WO99/52549 (1999-10-01), None
patent: WO 01/08495 (2001-02-01), None
patent: WO 01/14411 (2001-03-01), None
patent: WO 01/28552 (2001-04-01), None
patent: WO 02/28426 (2002-04-01), None
MMWR Recomm Rep. Apr. 30, 1999;48(RR-4):1-28 [No authors listed], Table 1 only.
Ball et al, “An assessment of thimerosal use in childhood vaccines”, Pediatrics, vol. 107, No. 5, May 2001 pp. 1147-1154.
Bernard et al., “Autism: A novel of mercury poisioning”, Medical Hypotheses, vol. 56, No. 4, Apr. 2001, pp. 462-471.
Brown et al., “Vaccinator device for delivery propellant-driven aerosols ofStreptococcus suisbacterin into the respiratory tracts of swine”, Vaccine, Butterworth Scientific, Guildford, GB, vol. 15, No. 11, Aug. 1, 1997, pp. 1165-1173.
Ellis, “Technologies for the design, discovery, formulation and administration of vaccines”, Vaccine, Butterworth Scientific, Guildford, GB, vol. 19, No. 17-19, Mar. 21, 2001, pp. 2681-2687.
Goetsch et al., “BBG2Na an RSV subunit vaccine candidate intramuscularly injected to human confers protection against viral challenge after nasal immunication in mice”, Vaccine, Butterworth Scientific Guildford, GB, vol. 19, No. 28-29, Jul. 16, 2001, pp. 4036-4042.
Newman et al., “Use of nonionic block copolymers in vaccines and therapeutics”, Critical Reviews in Therapeutic Drug Carrier Systems, United States 1998, vol. 15, No. 2, 1998, pp. 89-142.
Ott et al., “Enhancement of humoral response against human influenza vaccine with the simple submicron oil/water emulsion adjuvant MF59”, Vaccine, Butterworth Scientific., Guildford, GB, vol. 13, No. 16, Nov. 1, 1995, pp. 1557-1562.
Porschmann et al., “Application of surfactants to the supercritical fluid extraction of nitroaromatic compounds from sediments”, Journal of Chromatography A, Elsevier Science, NL, vol. 816, No. 2, Aug. 14, 1998, pp. 221-232.
Poryvaev et al., “The effect of conditions of storage and composition of viral material on lipid peroxidation of the viral envelope and inactivation of the invluenza virus”,Voprosy virusologii, Russia, vol. 40, pp. 62-65, 1995.
Gimmi Edward R.
Hecht Elizabeth J.
Hill Myron G.
Saechsisches Serumwerk Dresden Branch of SmithKline Beecham Phar
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