Inflammatory bowel disease preventive and curative agent contain

Details Inflammatory bowel disease preventive and curative agent contain Inflammatory bowel disease preventive and curative agent contain

1991-07-05

1993-08-24

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514400, 514867, A61K 31555

Patent

active

052389316

ABSTRACT:
An agent for the prevention and treatment of inflammatory bowel disease (IBD) containing at least one of zinc L-carnosine salts and complexes as an active ingredient. A use of the zinc L-carnosine salts or complexes and a therapeutic method of IBD by using the same are also disclosed.

REFERENCES:
Drugs of the Future, vol. 14, No. 12, 1989, pp. 1176-1177, "Z-103".
Gastroenterology, vol. 98, No. 5, May 12-18, 1990, part 2 of 2 parts, p. A94, M. Nakajima, et al., "Z-103, A New Antiulcer Agent, Inhibits Not Only Urease Activity But Also Campylobacter Pylori Growth".
Patent Abstracts of Japan, vol. 8, No. 122 (C-227) [1559], Jun. 8, 1984, & JP-A-59-33270, Feb. 23, 1984, H. Fujimura, et al., "Zinc Salt of Carnosine and Preparation Thereof".
Patent Abstracts of Japan, vol. 9, No. 112, (C-281) [1835], May 16, 1985, & JP-A-60-60-4172, Jan. 10, 1985, H. Fujimura, et al., "Zinc Hydroxide Salt of Carnosine and Its Preparation".
Patent Abstracts of Japan, vol. 15, No. 133 (C-820) [4661], Apr. 2, 1991 & JP-A-3-17022, Jan. 25, 1991, T. Yoshikawa, et al., "Remedy for Pancreatitis".
Akira Terano, "Mechanistic Aspects of Gastric Cytoprotection-A Review-, " Gastroenterologia Japonica, vol. 27, No. 2 (1992).
Robert D. Zipser, MD, "Mediators of Inflammation in Inflammatory Bowel Disease," Digestive Diseases and Sciences, vol. 33, No. 3, pp. 4S-5S (Mar. 1988 Supplement).

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