Infectious cDNA clone of GB virus B and uses thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S023700, C536S023720, C435S069100, C435S235100, C435S239000, C435S320100

Reexamination Certificate

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07129342

ABSTRACT:
The present invention relates to nucleic acid sequence which comprises the genome of an infectious GB virus B clone. The invention also relates to the use of the nucleic acid sequence of the infectious GB virus B clone to indirectly study the molecular properties of HCV, and in the production of HCV/GBV-B chimeras. The invention further relates to the use of the infectious nucleic acid sequence of GB virus B clone and the HCV/GBV-B chimeras in the development of vaccines and therapeutics for HCV.

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patent: WO 00/73466 (2000-12-01), None
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Yanagi, Masayuki et al, “In vivo analysis of the 3′ untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone.” Proceedings of the National Academy of Sciences of the United States 96:5 (pp. 2291-2295) Mar. 1999.
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Official Communication from the European Patent Office corresponding to application EP 00 939 534.4, 2004.

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