Infectious bursitis vaccine

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

Reexamination Certificate

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C435S236000

Reexamination Certificate

active

09355374

ABSTRACT:
The present invention is concerned with isolated infectious bursitis (or bursal) disease virus(es) and a vaccine containing said virus(es) which is capable of protecting poultry against disease caused by infectious bursitis virus, characterized in that the vaccine virus(es) has/have the combined properties of, upon administration to a chicken, causing a reduction in the bursal size, expressed as bursa/body weight ratio, of less than 55%, and the capability to protect poultry having an ELISA antibody titer of at least about 500.

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patent: 5192539 (1993-03-01), Van Der Marel et al.
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Murphy, F. A., 1996, “Virus Taxonomy”, inFields Virology, Third Edition, eds. Fields, B. N., et al., Lippincott-Raven Publishers, Philadelphia, p. 19.
Kouwenhoven et al., Poultry Health Institute, Proceedings 19thWorld's Poultry Congress, Amsterdam Sep. 19-24, 1992, vol 1, pp 465-468, Control of Very Virulent Infectious Bursal Disease (Gumboro Disease) in the Netherlands with So Called “Hot” Vaccines.
Lasher et al., World's Poultry Science Journal, vol 50, Jul. 1994, pp 133-166, Infectious Bursal Disease.
Lukert et al., Diseases of Poultry, Ninth Edition, Iowa State University Press 1991, pp 648-663, Infectious Bursal Disease.

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