Infectious bursal disease virus

Details Infectious bursal disease virus Infectious bursal disease virus

1992-09-15

1996-05-21

Mosher, Mary E.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

424816, 4352351, 435236, 435237, 435238, 435239, A61K 3912, C12N 700, C12N 702, C12N 704

Patent

active

055187242

ABSTRACT:
A new virus not neutralized or bound by monoclonal antibodies which are group neutralizing to all IBDV vaccines of current art, and capable of inducing infectious bursal disease in poultry is identified, in essentially pure form. A test kit, and assay for the presence of the virus is disclosed, together with the vaccine incorporating the virus. A monoclonal antibody Mab 50, which neutralizes the virus, form the basis of an alternative vaccine.

REFERENCES:
patent: 4530831 (1985-07-01), Lutticken et al.
patent: 4824668 (1989-04-01), Melchoir et al.
patent: 5064646 (1991-11-01), Snyder et al.
Bowie et al, Science 247:1306-1310 Mar. 1990.
Kumar et al. PNAS 87:1337-41 Feb. 1990.

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