Infectious bovine rhinotracheitis virus insertion mutants, vacci

Details Infectious bovine rhinotracheitis virus insertion mutants, vacci Infectious bovine rhinotracheitis virus insertion mutants, vacci

1995-02-22

1997-02-11

Guzo, David

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 936, 4351723, 4352351, 4353201, A61K 39265, A61K 3576, C12N 700, C12N 701

Patent

active

056018169

ABSTRACT:
The present invention relates to infectious bovine rhinotracheitis viruses which fail to produce any functional thymidine kinase as a result of an insertion in the thymidine kinase gene, vaccines against infectious bovine rhinotracheitis containing the same and methods for production and use of same. The present invention also relates to infectious bovine rhinotracheitis-based viral vectors useful for the coexpression of foreign genes.

REFERENCES:
patent: 4569840 (1986-02-01), Kit
patent: 4703011 (1987-10-01), Kit
patent: 4753884 (1988-06-01), Kit
patent: 4824667 (1989-04-01), Kit et al.
patent: 5128129 (1992-07-01), Kit
Shih et al., PNAS, vol. 81, pp. 5867-5870, Sep. 1984.
Liu et al., Gene, vol. 44, pp. 279-285, 1986.
Kit et al, Vaccines, 91 (1991).
Kit et al, J. Vet. Diag. Invest., 2:14-23 (1990).
Fenner et al, Veterinary Virology, Academic Press, Inc., pp. 353-356 (1987).
Ben-Porat et al, Virol., 154:325-334 (1986).
Zuckerman et al, Virol., 64:802-812 (1990).
Zwaagstra et al, J. Virol., 64:5019-5028 (1990).
Murphy et al, J. Biol. Chem., 259:10208-10211 (1984).
Bhat et al, Mol. Cell. Biol., 3:1996-2005 (1983).
Bhat et al, J. Virol., 56:750-756 (1985).
Bachmann et al, J. Gen. Virol., 67:2587-2594 (1986).
Grosschedl et al, Cell, 41:885-897 (1985).
Kit, Microbiological Sciences, 2:369-375 (1985).
Kit, in Immunobiology of Proteins and Peptides V, Atassi, Ed., (Plenum Publishing Corp., 1989), pp. 219-236.
Kit, in Technological Advances in Vaccine Development, pp. 183-195 (1988).

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