Infection-resistant compositions, medical devices and surfaces a

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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523112, A61F 202

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active

056163380

ABSTRACT:
A method of preparing an infection-resistant medical device comprising one or more matrix-forming polymers selected from the group consisting of biomedical polyurethane, biomedical silicones and biodegradable polymers, and antimicrobial agents, especially a synergistic combination of a silver salt and chlorhexidine (or its salts); also disclosed are medical devices having the synergistic composition therein or compositions thereon.

REFERENCES:
patent: 3705938 (1972-12-01), Hyman et al.
patent: 4381380 (1983-04-01), LeVeen et al.
patent: 4592920 (1986-06-01), Murtfeldt
patent: 4603152 (1986-07-01), Laurin et al.
patent: 4675347 (1987-06-01), Mochizuki et al.
patent: 4677143 (1987-06-01), Laurin et al.
patent: 4853978 (1989-08-01), Stockum
patent: 4925668 (1990-05-01), Khan et al.
Solomon et al., J. Controlled Release (1987) pp. 343-352 "Antibiotic Realing Polymers".
Lazarus et al., J. Biomed. Mater. Res. (1971) vol. 5, pp. 129-138 "A Hydrophilic Polymer-Coated Antimicrobial Urethral Catheter".
Szycher, "Controlled Delivery of Topical Antibiotics", Novel Drug Delivery Technologies Conference pp. 13.1-13.14.
Bayston et al., J. Clin. Pathol. (1981) 198; 134 pp. 1057-1062 "Antimicrobial activity of silicone rubber used in hydrocephalus shunts . . . ".
Van Noort et al., J. Biomedical Materials Research, (1979) vol. 13, pp. 623-630 "Mechanical properties of antibacterial silicone rubber for hydrocephalus shunts".
Brook et al., Biomaterials, (1986) vol. 7, pp. 292-296 "Controlling drug release from acrylic polymers: In vitro studies . . . ".
Coventry et al., J. of Clinical Periodontology, (1982) vol. 9, pp. 129-133 "Experimental use of a slow release device employing chlorhexidine gluconate . . . ".
Tuominen et al., Annals of Clinical Research, (1981) vol. 13, pp. 425-528 "The effect of local antiseptic, chlorhexidine, in preventing infection . . . ".
Harper et al., Paraplegia, (1983) vol. 21, pp. 86-93 "Simple additives to increase the activity of chlorhexidine digluconate . . . ".

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