Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1994-09-14
1997-11-11
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514 7, 514 23, 514 60, 514556, 514560, A61K 31195
Patent
active
056864914
ABSTRACT:
The present invention provides an infant formula for infants with metabolic disorders in fatty acid catabolism such as medium-chain acyl-CoA dehydrogenase deficiency (MCAD), long-chain acyl-CoA dehydrogenase deficiency (LCAD), short-chain acyl-CoA dehydrogenase deficiency (SCAD), multiple acyl-CoA dehydrogenase deficiency (MADD), Sudden Infant Death Syndrome (SIDS) and failure to thrive syndrome. The present invention also provides an assay for diagnosing children and infants with metabolic disorders such as failure to thrive syndrome; a method for treating failure to thrive syndrome; and a process for normalizing the lipid content of the mitochondrial membrane. In particular, the present invention provides an infant formula containing 90-130 cals/Kg which comprises (a) 2.5-3.5 g/Kg protein; (b) carbohydrate; (c) fat; and (d) .gtoreq.500 mg carnitine, wherein the ratio of carbohydrate to fat is greater than or equal to 60:40.
REFERENCES:
patent: 4753926 (1988-06-01), Lucas et al.
patent: 4920098 (1990-04-01), Cotter et al.
Medline Abstract, AN:87209982, (Jun. 1987), Winter, S.C. et al., Am J Dis Child, (Jun. 1987) 141(6) pp. 660-665.
Cintins Marianne M.
Moezie M.
Sigma-Tau Pharmaceuticals, Inc.
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