Inert matrix based on polycaprolactone for the oral administrati

Details Inert matrix based on polycaprolactone for the oral administrati Inert matrix based on polycaprolactone for the oral administrati

1984-12-26

1986-12-16

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

514951, A61K 3174

Patent

active

046296247

ABSTRACT:
The present invention relates to a new inert matrix having adjustable porosity and hardness.
This matrix comprises polycaprolactone having an average molecular weight of between 2000 and 70,000, which is in the form of agglomerated grains having an average diameter of between 50 and 500 .mu.m and has a degree of crystallinity of at least 75%. The invention relates to the method for the preparation of a porous galenic form by means of the said matrix.

REFERENCES:
patent: 3773919 (1973-11-01), Boswell et al.
patent: 3929937 (1975-12-01), Clendinning et al.
patent: 4148871 (1979-04-01), Pitt et al.
patent: 4264574 (1981-04-01), Cherqui et al.
Chemical Abstracts, vol. 92, No. 16, Apr. 21, 1980, abstract 92: 135249h.

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