Industrial process for the synthesis of isobutyl methyl...

Details Industrial process for the synthesis of isobutyl methyl... Industrial process for the synthesis of isobutyl methyl...

2006-06-13

2006-06-13

Morris, Patricia L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07060838

ABSTRACT:
Synthetic process of isobutyl methyl 1,4,-dihydro-2,6-dimethyl-4-(2-nitrophenyl)3,5-pyridine dicarboxylate (Nisoldipine) comprising on the reaction of isobutyl 2-(2-nitrobenzylidene)acetoacetate with methyl 3-aminocrotonate in an apolar solvent.

REFERENCES:
patent: 4154839 (1979-05-01), Wehinger et al.
patent: 4600778 (1986-07-01), Teller et al.

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