Industrial process for obtaining an aryloxypropanolamine

Details Industrial process for obtaining an aryloxypropanolamine Industrial process for obtaining an aryloxypropanolamine

1990-05-16

1992-01-21

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C07C20914

Patent

active

050829696

ABSTRACT:
Industrial process for obtaining an aryloxypropanolamine of chemical name 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol, characterized in that it comprises the following operating phases. By reacting 4-(2-methoxyethyl)phenol with epichlorohydrin in an alkaline aqueous medium at temperatures of between 0.degree. and 25.degree. C. a crude reaction product composed to the extent of 75-80% of 3-[4-(2-methoxyethyl)phenoxy]-1,2-epoxypropane and to the extent of 15-20% of 1-[4-(2-methoxyethyl)phenoxy]-3-chloro-2-propanol is obtained, after the appropriate extractions and washings, both compounds being suitable for reacting with isopropylamine in an aqueous medium and at temperatures ranging between 0.degree. and 30.degree. C. to obtain the desired aryloxypropanolamine of formula I.

REFERENCES:
patent: 3780081 (1973-12-01), Le Count et al.
patent: 3998790 (1976-12-01), Brandstrom et al.
patent: 4258062 (1981-03-01), Jonas et al.
patent: 4396629 (1983-08-01), Phillion
patent: 4515814 (1985-05-01), Wick et al.
patent: 4760182 (1988-07-01), Ippolito et al.

Affiliated with

Also associated with

Rating

Industrial process for obtaining an aryloxypropanolamine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Industrial process for obtaining an aryloxypropanolamine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Industrial process for obtaining an aryloxypropanolamine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-116709