Industrial antimicrobial:uses for 2-(2-bromo-2-nitroethenyl)-fur

Chemistry: fertilizers – Processes and products – Forms or conditioning

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514471, 507132, A01N 4308

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active

050909908

ABSTRACT:
2-(2-bromo-2-nitroethenyl)-furan can be used as an antimicrobial in broad spectrum of uses. A novel process for preparing 2-(2-bromo-2-nitroethenyl)-furan has been found in which furfural is reacted with bromonitromethane using a primary amine or primary amine salt as a catalytic agent to produce an intermediate product which is dehydrated in the presence of acid to the desired product. An antimicrobial composition comprising 2-(2-bromo-2-nitroethenyl)-furan and a carrier is also disclosed.

REFERENCES:
Nazarova "Concerning B. Nibovinyl-5-Substituted Furans" Zhur. Cebshcski Khim., vol. 24, 1954, pp. 589-592.
Nazarova et al., "Synthesis of Some Furylnitroolefins with Potential Biological Activity" Potemkin Khim. Form. Zh. Volle, 1972, pp. 629-632.
Gruntfest et al., "Physiochemical Properties and Reactivity". . . etc. Zh. Org. Kh., vol. 8, 1972, pp. 405-411.
Latif et al., "Biological Polyactive Compounds, Nitrovinylfurans . . . " etc. Journal of Prukt. Chemie., vol. 315, 1973, pp. 419-426.
Schales, et al., "Arylnitroalkenes: A New Group of Antibacterial Agents" J. Am. Chem. Soc. 74, 4486 (1952).

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