Induction of tolerance with modified immunogens

Details Induction of tolerance with modified immunogens Induction of tolerance with modified immunogens

1991-01-23

1999-03-23

Smith, Lynette F.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Animal or plant cell

424 88, 530350, A01N 6300

Patent

active

058855700

ABSTRACT:
A method is provided for inducing tolerance to T-cell mediated immunity. Particularly, tolerance is induced in a recipient mammal to a transplanted organ or tissue. Tolerance is induced by treating the recipient mammal with a MHC antigen which has been modified to render an immunosuppressive effect.

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