Induction of immunological tolerance

Details Induction of immunological tolerance Induction of immunological tolerance

1978-08-28

1983-06-14

Schain, Howard E.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

424 78, 424 85, 424 88, 525420, 528310, C08G 6948, C08G 6950

Patent

active

043884415

ABSTRACT:
Immunosuppressive agents which are conjugates of an antigen linked to a D glutamic acid:D-lysine copolymer are disclosed. Also disclosed are methods of preparing the conjugates and therapeutic methods for inducing immunological tolerance to antigens.

REFERENCES:
patent: 3794630 (1974-02-01), Mullan et al.
Noss et al., J. of Expl. Med., vol. 138, (1973), pp. 312-317.
Eshhar et al., J. Immunol., vol. 114, No. 2, (1975), pp. 872-876.
Chiorazzi et al., Proc. Natl. Acad. Sci. U.S.A., vol. 73, No. 6, Jun. 1976, pp. 2091-2095.
Bitter-Suermann et al., Chemical Abstracts, vol. 83, 129,895p, (1975).
Mosier et al., Chemical Abstracts, vol. 83, 191,237d, (1975).

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