Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1996-11-13
2000-07-04
Hutzell, Paula K.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435325, 435 691, 536 231, 530350, 514 12, A61K 3800, C12N 1585
Patent
active
060840854
ABSTRACT:
Individuals having tumors are treated with pharmaceutical compositions comprising expression vectors, preferably adenovirus or retroviruses, comprising nucleic acid molecules encoding soluble IGF-1R. Such vectors express soluble IGF-1R in tumor cells resulting in reversal of the transformed phenotype, induction of apoptosis, and inhibition of tumorigenesis.
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C
Baserga Renato
D'Ambrosio Consuelo
Ferber Andre
Resnicoff Mariana
Davis Minh-Tam
Hutzell Paula K.
Thomas Jefferson University
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