Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1994-06-24
1997-08-19
Low, Christopher S.F.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
424 932, 424 931, 514 44, 435189, 435191, 4353201, 4351723, 4352351, 536 231, 536 232, 536 235, 935 60, 935 22, 935 32, 935 9, A61K 4800
Patent
active
056585659
ABSTRACT:
The present invention discloses a full-length human hepatocyte iNOS cDNA clone and various gene therapy applications utilizing an iNOS DNA sequence. In preferred embodiments of the disclosed invention, iNOS-directed gene therapy involves specific targeting of a DNA sequence encoding a protein or protein fragment with iNOS biological activity for treating vascular diseases and disorders, antitumor applications and in response to certain microbial infections.
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Billiar Timothy R.
Geller David A.
Nussler Andreas K.
Simmons Richard L.
Tzeng Edith
Low Christopher S.F.
University of Pittsburgh of the Commonwealth System of Higher Ed
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