Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1993-07-29
2000-12-26
Eyler, Yvonne
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
5303877, 5303888, C07K 100, C07K 1400, C07K 1700, C07K 1600
Patent
active
061661791
ABSTRACT:
Monoclonal antibody E1/6, or fragments thereof, blocks adhesion to the vascular endothelium of certain pathophysiological cells. Monoclonal antibody E1/6, or fragments thereof, and the glycoprotein recognized by the E1/6 antibody, are used pharmaceutically, therapeutically, and diagnostically in the treatment of these pathophysiological disorders. Compositions, methods of treating, and methods of diagnosing are disclosed.
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Bevilacqua et al. J. Clin. Invest. 76:2003-2011, 1985.
Vanderheide et al. J. Exp. Med. 175:1433-1442, 1992.
Sherman-Gold, Genetic Engineering News, Jul. 1993, pp. 6, 7, 14.
Herbert et al., Eds. Dictionary of Immunology, Blackwell Scientific Publications, 1985, p. 77.
Bevilacqua Michael P.
Rice G. Edgar
Brigham & Women's Hospital
Eyler Yvonne
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