Indolythiadiazines for treating heart failure

Details Indolythiadiazines for treating heart failure Indolythiadiazines for treating heart failure

1989-07-13

1991-09-24

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544 6, 544 8, C07D28516, A61K 3154

Patent

active

050514172

ABSTRACT:
A compound of formula (I) or a pharmaceutically acceptable salt thereof, ##STR1## in which, R.sub.1 is hydrogen or lower alkyl;

REFERENCES:
patent: 4678785 (1987-07-01), Ao et al.
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Hodges et al. "Chemical and Biological" CA 69:43883g (1968).
Walker et al. "Synthesis of New 3 . . ." CA 63:11563h (1965).
Youngdale et al. "Synthesis and Phamacological . . ." CA 61:11957e (1964).
Robertson et al., "Dihydro Pyridazinone Cardiotonics : Synthesis and Intropic Activity of S'-(1,4,5,6-Tetrahydro-6-oxo-3-Pyridazinyl) Spiro [Cycloalkane-1,3'-[3H] Indol]-2'(1'H)-Ones," J. Med. Chem. 1987 (30) 824-829.

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