Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1979-09-05
1982-03-02
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
26032615, 260315, 424238, 424273P, 424270, 424326, 546145, 546176, 548154, A61K 3140, C07D20914
Patent
active
043178324
ABSTRACT:
Compounds corresponding to the formula ##STR1## are disclosed, wherein Alk represents a C.sub.2 -C.sub.5 -alkylene groups optionally substituted by a hydroxy group and Ar represent an optionally substituted phenyl, naphthyl, tetrahydronaphthyl, indanyl or indenyl radical or a monocyclic or condensed bicyclic or tricyclic heterocyclic radical which is optionally substituted, the heterocyclic radical consisting of individual rings having 5 or 6 members and optionally containing from 1 to 4 hetero atoms, and the acid addition salts thereof. A process for producing these compounds is also disclosed. These substituted aminoalkyl guanidines block the .beta.-receptors of the adrenergic nerve system, and also reduce blood pressure.
REFERENCES:
patent: 3317570 (1967-05-01), Claassen
patent: 3471515 (1969-10-01), Troxler et al.
patent: 3499003 (1970-03-01), Welstead
patent: 3501497 (1970-03-01), Bell
patent: 3542873 (1970-11-01), Faith
patent: 3644353 (1972-02-01), Lunts et al.
patent: 3821301 (1974-06-01), Klingler
patent: 4144340 (1979-03-01), Ottermans
Kleemann Axel
Klingler Karl-Heinz
Stroman Fritz
Thiemer Klaus
Daus Donald G.
Springer D. B.
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