Indoloquinolines, intermediates and processes

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260246B, 2602472A, 2602475FP, 260268PC, 260283SY, 260283CN, 260287C, 260289K, 26032613R, 26032614, 424250, 424258, 42424856, 42424857, 42424858, C07D47104

Patent

active

040148831

ABSTRACT:
Derivatives of 7H-indolo[2,3-c]quinolin-6(5H)-one and 7H-indolo[2,3-c]quinoline, prepared, inter alia, from the corresponding 3-azido-4-phenylcarbostyrils or corresponding N-(lower alkylamino)-3-(2-fluorophenyl)-indole-2-carboxamides, are described. The end products of the invention are useful as anti-tumor agents, i.e., they inhibit the growth of transplantable tumors.

REFERENCES:
patent: 3326920 (1967-06-01), Stanabach et al.
patent: 3420834 (1973-11-01), Muller et al.
Winterfeldt et al., Angew Chem. Internat. Edit., vol. 17 (1968) p. 466.
Peterson et al., Acta Chem. Scand., vol. 23 (1969) pp. 971-974.

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