Indoloquinazolinones

Details Indoloquinazolinones Indoloquinazolinones

2005-11-15

2005-11-15

McKenzie, Thomas C. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S252160, C514S257000, C544S115000, C544S246000

Reexamination Certificate

active

06964960

ABSTRACT:
The invention provides compounds of formula (I) wherein R is as defined in the description, and the preparation thereof. The compounds of formula (I) are useful as pharmaceuticals, for use in the treatment of any state associated with high levels of activeted PARP.

REFERENCES:
patent: 5441955 (1995-08-01), Baker et al.
patent: 1309 485 (1973-03-01), None
patent: 1 428 488 (1976-03-01), None
patent: WO 95 24379 (1995-09-01), None
Abdelkarim GE, Gertz K, Harms C, Katchanov J, Dirnagl U, Szabo C, Endres M., Int J Mol Med. Mar. 2001;7(3):255-60, Medline Abstract PMID: 11179503.
Alexander Bürkle, BioEssays vol. 23, Issue 9, pp. 795-806.

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