Indolopyrrolocarbazole derivatives

Details Indolopyrrolocarbazole derivatives Indolopyrrolocarbazole derivatives

1994-06-08

1997-01-07

Kight, John

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 177, 536 187, 540545, C07H 1900, C07H 1922, A61K 3170

Patent

active

055918425

ABSTRACT:
Indolopyrrocarbazole derivatives such as exemplified by the following compound, ##STR1## have excellent antitumor activity as evidenced by in vitro proliferation inhibiting activity against mouse leukemia cell, human gastric cancer cell, human lung cancer cell and human colon cancer cell.

REFERENCES:
patent: 4552842 (1985-11-01), Nettleton et al.
patent: 4785085 (1988-11-01), Kaneko et al.
patent: 4808613 (1989-02-01), Kaneko et al.
patent: 4912107 (1990-03-01), Kleinschroth et al.
patent: 4923986 (1990-05-01), Murakat et al.
patent: 5015578 (1991-05-01), Schroeder et al.
patent: 5043335 (1991-08-01), Kleinschroth et al.
patent: 5073633 (1991-12-01), Schroeder et al.
patent: 5106864 (1992-04-01), Suda et al.
patent: 5158938 (1992-10-01), Lam et al.
patent: 5227396 (1993-07-01), Laakso et al.
patent: 5326754 (1994-07-01), Lam et al.
patent: 5344823 (1994-09-01), Lam et al.
Joyce, et al. J. Org. Chem. 52, No. 7 (1987) pp. 1177-1185.
Kaneko, et al. J. Antibiotics, vol. XL111, No. 1 (1989) pp. 125-127.
47th Japan Society of Cancer General Meeting Article (1988) pp. 12-15 (Eng. Abstr).
Kojiri, et al. J. Antibiotics, vol. 44, No. 7 (Jul. 1991) pp. 723-728.
Hughes, et al. J. Chem. Soc. Perkin Trans. 1, (1990) pp. 2475-2480.
Reynolds, et al. J. Am. Chem. Soc. 60, (1938) pp. 2559-2561.
4Bush, et al. J. Antibiotics, vol. 40, (1987) pp. 668-678 (Eng. Abstr).

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