Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-12-12
2006-12-12
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S235200, C514S249000, C514S252060, C514S323000, C514S339000, C514S338000, C514S377000, C514S383000, C514S394000, C514S217080, C546S201000, C546S277700, C548S266400, C548S454000, C548S455000, C548S468000, C540S575000, C544S144000, C544S235000, C544S238000
Reexamination Certificate
active
07148249
ABSTRACT:
The present invention relates to heterocyclically substituted indolinones of general formulawhereinR1to R5and X are defined as in claim 1, the tautomers, the diastereomers, the enantiomers, the mixtures thereof, the prodrugs thereof and the salts thereof, particularly the physiologically acceptable salts thereof which have valuable pharmacological properties, in particular an inhibiting effect on various receptor tyrosine kinases and cyclin/CDK complexes and on the proliferation of endothelial cells and various tumour cells, pharmaceutical compositions containing these compounds, their use and processes for preparing them.
REFERENCES:
patent: 6762180 (2004-07-01), Roth et al.
patent: 6858641 (2005-02-01), Roth et al.
patent: WO 01/16130 (2001-03-01), None
patent: WO 01/27080 (2001-04-01), None
patent: WO 01/27081 (2001-04-01), None
Kandile, N. G. et al. Revue Roumaine de Chimie 1991, 36(1-3), 245.
Copy of International Search Report Reference #PCT/EP 03/09978.
Heckel Armin
Hilberg Frank
Kley Joerg
Lehmann-Lintz Thorsten
Lotz Ralf R. H.
Boehringer Ingelheim Pharma GmbH & Co. KG
Devlin Mary-Ellen M.
Morris Michael P.
Nolan Jason M.
Saeed Kamal A.
LandOfFree
Indolinones substituted by heterocycles, the preparation... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Indolinones substituted by heterocycles, the preparation..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Indolinones substituted by heterocycles, the preparation... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3700064