Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1999-03-26
2000-03-28
Stockton, Laura L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514397, 514414, 546143, 5483121, 548465, A61K 31404, A61K 314725, C07D40312, C07D40112
Patent
active
060432543
ABSTRACT:
The present invention relates to indolinones of general formula ##STR1## wherein R.sub.1 to R.sub.3 are defined in claim 1, the isomers and the salts thereof, particularly the physiologically acceptable salts thereof which have valuable pharmacological properties, particularly an inhibiting effect on various kinases and cycline/CDK complexes and on the proliferation of various tumour cells, pharmaceutical compositions containing these compounds, their use and processes for preparing them.
REFERENCES:
patent: 4861880 (1989-08-01), Howard, Jr. et al.
Grell Wolfgang
Haigh Robert
Heckel Armin
Himmelsbach Frank
Redemann Norbert
Boehringer Ingelheim Pharma KG
Devlin Mary-Ellen M.
Raymond Robert P.
Stempel Alan
Stockton Laura L.
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