Indoleacetic acid ester derivatives

Details Indoleacetic acid ester derivatives Indoleacetic acid ester derivatives

1977-06-07

1979-08-21

Raymond, Richard

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

26032613A, 424263, 424274, C07D20928, C07D21379

Patent

active

041654285

ABSTRACT:
The present invention relates to the indoleacetic acid ester derivatives of the following general formula: ##STR1## WHEREIN N REPRESENTS AN INTEGER FROM ONE TO 3; R is selected from the group consisting of hydroxyl, halogen, trihalomethyl, alkoxy, acyloxy, substituted phenyl, pyridyl and substituted pyridyl. These compounds possess a high degree of pharmacological activities such as analgetic, anti-inflammatory and anti-pyretic activities as well as low side effects on the gastrointestinal tracts when given orally and topically, and therefore they may be useful as analgesics, anti-inflammatories and anti-pyretics for internal and external use.

REFERENCES:
patent: 3271394 (1966-09-01), Shen
patent: 3470203 (1969-09-01), Gal et al.
patent: 3910952 (1975-10-01), Boltze et al.
The Merck Index, 8th Edition, p. 566, "Indomethacin".

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