Indoleacetic acid derivatives used as anti-inflammatories

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548500, A61K 31405

Patent

active

048682012

ABSTRACT:
1-(fluoro- or perfluoro lower alkyl-substituted benzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid carboxymethyl ester is found to have antiinflammatory and analgestic activity with less side effects on gastrointestinal traces than its homologue, acematacin or indometacin.

REFERENCES:
patent: 3468907 (1969-09-01), Sherlock
patent: 4104278 (1978-08-01), Boltze et al.
patent: 4459415 (1984-07-01), Boltze

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