Indole-type derivatives as inhibitors of p38 kinase

Details Indole-type derivatives as inhibitors of p38 kinase Indole-type derivatives as inhibitors of p38 kinase

2007-05-22

2009-02-10

Wilson, James O. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S400000, C548S452000, C548S469000

Reexamination Certificate

active

07488744

ABSTRACT:
The invention is directed to methods to inhibit p38-α kinase using compounds comprising a phenyl or thienyl coupled through a piperidine or piperazine nucleus to an indole residue wherein the indole residue mandatorily has a substituent on the ring nitrogen which is an amino or substituted amino group.

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